Fluence compensation in raster-scan optoacoustic angiography

Modern optical imaging techniques demonstrate significant potential for high resolution in vivoangiography. Optoacoustic angiography benefits from higher imaging depth as compared to pure optical modalities. However, strong attenuation of optoacoustic signal with depth provides serious challenges for adequate 3D vessel net mapping, and proper compensation for fluence distribution within biotissues is required. We report on the novel approach allowing …