Optoacoustic Angiography and Diffuse Optical Spectroscopy for Experimental Oncology

Congratulations to the authors of the scientific result “Optoacoustic Angiography and Diffuse Optical Spectroscopy for Experimental Oncology” conducted by employees of the Department for Radiophysical methods in medicine of the Institute of Applied Physics of the Russian Academy of Sciences. Their work has been selected for presentation in the RAS report and has entered the …

Toward whole-brain in vivo optoacoustic angiography of rodents: modeling and experimental observations.

Cerebrovascular imaging of rodents is one of the trending applications of optoacoustics aimed at studying brain activity and pathology. Imaging of deep brain structures is often hindered by sub-optimal arrangement of the light delivery and acoustic detection systems. In our work we revisit the physics behind opto-acoustic signal generation for theoretical evaluation of optimal laser …

Quantitative techniques for extraction of blood oxygenation from multispectral optoacoustic

We report on the comparison of two approaches to the reconstruction of oxygen saturation (StO2) within blood vessels from multispectral optoacoustic (OA) measurements. The spatially-resolving approach is based on determination of the optical absorption coefficient µa from OA signal amplitudes, while the calibration-free approach is based on evaluation of the effective optical attenuation coefficient µeff derived from the in-depth …