The non-invasive measurement of blood oxygen saturation in blood vessels is a promising clinical application of optoacoustic imaging. Nevertheless, precise optoacoustic measurements of blood oxygen saturation are limited because of the complexities of calculating the spatial distribution of the optical fluence. In the paper error in the determination of blood oxygen saturation, associated with the …
Author: barinn
Cost-effective imaging of optoacoustic pressure, ultrasonic scattering, and optical diffuse reflectance with improved resolution and speed
The idea of a method of cost-effective upgrades from an acoustic resolution photoacoustic microscope to a triple-modality imaging system is validated using phantoms. The newly developed experimental setup is based on a diode pumped solid state laser coupled to a fiber bundle with a spherically focused polyvinylidene fluoride detector integrated into the center of a …
Simultaneous triple-modality imaging of diffuse reflectance, optoacoustic pressure and ultrasonic scattering using an acoustic-resolution photoacoustic microscope: feasibility study
The letter discusses the opportunity for cost-effective use of conventional optoacoustic hardware to realize additional imaging modalities such as ultrasonic microscopy and diffuse optical reflectometry within the same laser pulse. Optoacoustic methods for deep biomedical visualization are based on pulsed laser illumination of the internal tissue layers with scattered photons, however some of the back-scattered …
Simultaneous photoacoustic and optically mediated ultrasound microscopy: an in vivo study
We propose the use of thermoelastic (TE) excitation of an ultrasonic (US) detector by backscattered laser radiation as a means of upgrading a single-modality photoacoustic (PA) microscope to dual-modality PA/US imaging at minimal cost. The upgraded scanning head of our dual-modality microscope consists of a fiber bundle with 14 output arms and a 32MHz polyvinylidene …
Simultaneous photoacoustic and optically mediated ultrasound microscopy: phantom study
An experimental setup for combined photoacoustic (PA) and optically mediated ultrasound (US) microscopy is presented. A spherically focused 35 MHz polyvinylidene fluoride (PVDF) ultrasonic detector with a numerical aperture of 0.28, a focal distance of 9 mm, and a bandwidth (−6 dB−6 dB level) of 24 MHz was used to obtain PA and US data with a 3 mm imaging depth. A fiber-optic system was …
