Quantitative techniques for extraction of blood oxygenation from multispectral optoacoustic

We report on the comparison of two approaches to the reconstruction of oxygen saturation (StO2) within blood vessels from multispectral optoacoustic (OA) measurements. The spatially-resolving approach is based on determination of the optical absorption coefficient µa from OA signal amplitudes, while the calibration-free approach is based on evaluation of the effective optical attenuation coefficient µeff derived from the in-depth …